Liquid Biopsy to Discover Early Stage Cancer


In a world where cancer is the second leading cause of death, it’s important to have new ways that can help detect and treat these diseases early on. One such technique would be liquid biopsy- an innovative form of testing blood samples for signs of cancer.

Colorectal Polyp Clinical Decision Support Device

Colon cancer is the third leading cause of death from cancer in the United States. Colorectal cancer usually starts from polyps or other precancerous growths in the rectum or the colon (large intestine). As part of a colorectal cancer screening and surveillance plan, clinicians perform colonoscopies to detect changes or abnormalities in the lining of the colon and rectum. A colonoscopy involves threading an endoscope (thin, flexible tube with a camera at the end), through the rectum and throughout the entire length of the colon, allowing a clinician to see signs of cancer or precancerous lesions.

The team of clinicians at Encore Borland Groover Clinical Research (EBGCR) is exploring new ways to detect and prevent colon cancer.

Atopic Dermatitis

Atopic dermatitis is a chronic, inflammatory skin disease that results in widespread rashes and patches of itchy skin, most commonly around the neck, face, and eyes in adults. It is uniquely and strongly associated with an individual or family history of asthma, hay fever, food allergy, and other allergic diseases. The most common form of eczema, atopic dermatitis symptoms can cause discomfort, depression, and sleep disturbance.

DOES YOUR SKIN ITCH DUE TO ATOPIC DERMATITIS?

Consider Participating in this Clinical Study

YOU MAY BE ELIGIBLE IF*

• You are 18 – 80 years old

• Have received a medical diagnosis of moderate-to-severe Atopic Dermatitis (AD}(also known as Atopic Eczema} for at least 3 years

• Have tried topical (applied to the skin} treatments for AD, and they have not worked well, or you are unable to use them•

PARTICIPATION DETAILS

• Qualified participants will receive medication, lab tests and medical care related to the study at no cost

• Participants are eligible for compensation to cover the cost of time and travel

Atopic Dermatitis is a skin condition that causes intense itching as well as patches of red bumps, flakes, weepy, or thick, crusty skin across the face, neck, body, and/or arms/legs.

Learn more about a clinical trial for Atopic Dermatitis (Eczema)
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Prevent Colon Cancer

Early CRC detection saves lives.

Are you due for your next colonoscopy within the next 90 days? Join this study to help us develop a blood test that accurately and easily detects colorectal cancer (CRC). According to the CDC, early detection can dramatically improve survival rates. That’s why we are looking to validate a simple blood test for early CRC detection.

Contact Research

 

Physician Investigator
Photo of Bharat K Misra M.D.
Gastroenterologist and Research Director Encore Borland Groover Clinical Research (EBGCR)
Clinical Research Location 4800 Belfort Road Jacksonville FL 32256 Contact Research: 9046800871
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GERD Gastroesophageal Reflux Disease

Gastroesophageal Reflux Disease (GERD)

The most common symptoms of GERD are acid indigestion and heartburn.   Heartburn is normal.  Frequent and problematic heartburn should be reviewed with your gastroenterologist.

Patients with severe gastroesophageal reflux disease (GERD) may experience complications such as damage to the esophagus, Barrett’s esophagus or esophageal cancer.

Find out more about clinical studies for patients with GERD.

Contact Research

Physician Investigator
Photo of Bharat K Misra M.D.
Gastroenterologist and Research Director Encore Borland Groover Clinical Research (EBGCR)
Clinical Research Location 4800 Belfort Road Jacksonville FL 32256 Contact Research: 9046800871
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Eosinophilic Esophagitis EoE

The esophagus carries food and liquids from your mouth to the stomach. Eosinophilic esophagitis (EoE) is a chronic disease of the esophagus.  If you have EoE, white blood cells called eosinophils build up in your esophagus. This can cause damage and inflammation causing pain and may lead to trouble swallowing and food getting stuck in your throat or dysphagia.

EoE is a newly recognized disease and some who think that they have reflux (GERD) may actually have EoE.

You may be eligible for a clinical research study if you have a confirmed diagnosis of eosinophilic esophagitis (EoE), eosinophilic gastritis and/or
eosinophilic duodenitis (EG/EoD).

Contact Research

ClinicalTrials.gov Study Details

 Eosinophilic Esophagitis
Clinical Research Protocol AK002-014 A Phase 2/3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of AK002 in Adult and Adolescent Patients with Active Eosinophilic Esophagitis

Photo of Ali Lankarani M.D.
Gastroenterologist Encore Borland Groover Clinical Research
Clinical Research Location 4800 Belfort Road Jacksonville FL 32256 Contact Research: (904) 680-0871
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Photo of Michael Ibach MD
Gastroenterologist Encore Borland Groover Clinical Research
Contact Research: 9046800871
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Eosinophilic Gastroenteritis/Duodenitis

Eosinophilic Gastroenteritis


Eosinophilic gastroenteritis is a rare disease in which a type of white blood cell, the eosinophil, causes injury and inflammation to the stomach and the small intestine. Eosinophilic gastroenteritis may affect both adults and children. The cause is unknown.

Symptoms:

  • Vomiting, nausea, diarrhea
  • Difficulty feeding and/or gaining weight
  • Poor growth and weight loss
  • Abdominal pain
  • Bloody diarrhea
  • Malnutrition
  • Fatigue

Current Clinical Trials


ClinicalTrials.gov Study Details
Eosinophilic Gastritis and/or Eosinophilic Duodenitis (Formerly Referred to as Eosinophilic Gastroenteritis) (ENIGMA 2)
Clinical Research Protocol AK002-016 A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of AK002 in Patients with Moderately to Severely Active Eosinophilic Gastritis and/or Eosinophilic Duodenitis (formerly referred to as Eosinophilic Gastroenteritis) Who Have an Inadequate Response with, Lost Response to, or Were Intolerant to Standard Therapies

Clinical Research Protocol AK002-019 A Prospective Study to Identify the Prevalence of Eosinophilic Gastrointestinal Diseases and Elevated Tissue Mast Cells among Patients with Chronic Gastrointestinal Symptoms

Dr. Lankarani reviews the link between Eosinophilic Gastroenteritis and IBS.

Contact Research

Photo of Ali Lankarani M.D.
Gastroenterologist Encore Borland Groover Clinical Research
Clinical Research Location 4800 Belfort Road Jacksonville FL 32256 Contact Research: (904) 680-0871
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Photo of Ben Pineau M.D., F.R.C.P.
Gastroenterologist Encore Borland Groover Clinical Research
Clinical Research Location 100 Whetstone Place Suite 300 St. Augustine FL 32086 Contact Research: (904) 680-0871 Website: Contact Dr. Pineau
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C. Difficile

C.  DIFF According to the CDC


Clostridioides difficile (also known as C. diff or CDIFF) is a bacterium that causes diarrhea and colitis (an inflammation of the colon).

It’s estimated to cause almost half a million illnesses in the United States each year.

About 1 in 6 patients who get C. diff will get it again in the subsequent 2-8 weeks.

Within a month of diagnosis, 1 in 11 people over age 65 died of a healthcare-associated C. diff infection.

PRISM-EXT: An Open-Label Extension of CP101 Trial Evaluating Oral FullSpectrum Microbiota® (CP101) in Subjects with Recurrence of Clostridium difficile Infection


Contact Research

 

Physician Investigator
Photo of Bharat K Misra M.D.
Gastroenterologist and Research Director Encore Borland Groover Clinical Research (EBGCR)
Clinical Research Location 4800 Belfort Road Jacksonville FL 32256 Contact Research: 9046800871
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NASH, Fatty Liver, Cirrhosis

Non Alcoholic Steatohepatitis (NASH) is a type of fatty liver disease, characterized by inflammation of the liver with concurrent fat accumulation in liver.

NASH is closely related to the triple epidemic of obesity, pre-diabetes, and diabetes.  If you are living with NASH you may qualify for a clinical research study.  

Join Encore Borland Groover Clinical Research (EBGCR) for a complimentary Fibroscan test for fatty liver. 

ClinicalTrials.gov Study Details
Liver-biopsy Proven NASH
A phase 2b randomized, double blind, placebo-controlled, multicenter study evaluating safety and efficacy of EDP-305 in subjects with liver-biopsy proven non-alcoholic steatohepatitis (NASH) (ARGON-2)

Contact Research
Photo of Ana Corregidor MD
Gastroenterologist Encore Borland Groover Clinical Research
Clinical Research Location 4800 Belfort Road Jacksonville FL 32256 Contact Research: (904) 680-0871
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Photo of Michael Herman M.D.
Gastroenterologist Fleming Island Center for Clinical Research
Clinical Research Location 1679 Eagle Harbor Parkway Suite D Fleming Island FL 32003 Contact Research: (904) 621-0390
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Photo of Linda Di Teodoro M.D.
Encore Borland Groover Clinical Research
Clinical Research Location 4800 Belfort Road Jacksonville FL 32003 Contact Research: 904-680-0871
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Crohn’s Disease

Inflammatory Bowel Disease (IBD)

Inflammatory bowel disease (IBD) is a term for two conditions (Crohn’s disease and ulcerative colitis) that are characterized by chronic inflammation of the gastrointestinal (GI) tract. Inflammation affects the entire digestive tract in Crohn’s disease and only the large intestine (also called the colon) in ulcerative colitis

Crohn’s symptoms can be constant and isolating. Our new clinical studies are investigating potential treatment options.

Learn more about current Crohn’s disease or Ulcerative Colitis research trials.

ClinicalTrials.gov Study Details
Crohn’s Clinical Trial ABBV M14-431
Clinical Study Protocol M14-431 A Multicenter, Randomized, Double-Blind, Placebo-Controlled Induction Study of the Efficacy and Safety of Upadacitinib (ABT-494) in Subjects with Moderately to Severely Active Crohn’s Disease Who Have Inadequately Responded to or are Intolerant to Biologic Therapy
Crohn’s Clinical Trial ABBV M14-433
Clinical Study Protocol M14-433 A Multicenter, Randomized, Double-Blind, Placebo-Controlled Induction Study of the Efficacy and Safety of Upadacitinib (ABT-494) in Subjects with Moderately to Severely Active Crohn’s Disease Who Have Inadequately Responded to or are Intolerant to Conventional and/or Biologic Therapies

ARENA: Principal Investigator: Dr. Munoz
Etrasimod S1P receptor modulator to treat Immune-mediated Inflammatory disorders. for Moderate to Severe Crohn’s Disease.

Treatment or conventional treatment. Etrasimod is a synthetic S1P receptor modulator given orally. 18-80 YOA


Contact Research

Physician Investigator

Photo of Mark Fleisher M.D.
Gastroenterologist Encore Borland Groover Clinical Research
Clinical Research Location 4800 Belfort Road Jacksonville FL 32256 Contact Research: 9046800871
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Photo of Juan Carlos Munoz M.D.
Gastroenterologist Encore Borland Groover Clinical Research
Contact Research: 9046800871
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Photo of Lindsey Merritt D.O.
Encore Borland Groover Clinical Research
Contact Research: 9046800871

Notes

Dr. Merritt helps patients understand and manage gastrointestinal disorders such as early GI malignancies, IBD, and pancreatic diseases, from diagnosis and staging to treatment. Dr. Merritt also practices general gastroenterology, including colorectal cancer screening and other gastrointestinal concerns including, the management of peptic ulcer disease, fatty liver, diarrhea, constipation, celiac disease, and SIBO.

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