Celiac Disease

Celiac Disease

Celiac disease is a multifaceted autoimmune disorder that affects approximately 1 in 100 individuals globally. Alarming statistics reveal that only 30% of celiac cases have been diagnosed accurately. This disorder is triggered by the consumption of gluten, which can damage the small intestine. Dr. Misra, an expert in the field, is researching celiac disease and evaluating various treatment options. Identifying and diagnosing celiac disease correctly is essential to prevent long-term complications and improve patient outcomes.

Presentation slides from Dr. Misra’s Learn with the Leaders: Celiac Disease.

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Physician Investigator
Photo of Bharat K Misra M.D.
Gastroenterologist and Research Director Encore Borland Groover Clinical Research (EBGCR)
4800 Belfort Road Jacksonville FL 32256 Contact Research: 9046800871
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Cirrhosis from NASH

NASH, or nonalcoholic steatohepatitis, is a liver condition that often goes unnoticed for years. However, it should not be taken lightly as it gradually worsens and can eventually lead to cirrhosis, a severe liver disease. Cirrhosis from NASH is becoming increasingly prevalent in the United States and is now one of the main causes of adult cirrhosis. This underscores the importance of early detection and appropriate medical management, which can help prevent further liver damage and the progression of the disease. If you suspect that you may be at risk for NASH, it is critical to speak with your healthcare provider and take the necessary steps to safeguard your liver health.

Join Encore Borland Groover Clinical Research (EBGCR) for a complimentary Fibroscan test for fatty liver. Be sure to take advantage of this opportunity to assess your liver health and take control of your well-being.

Bowel or Esophageal Strictures

Bowel or Esophageal Strictures

Bowel strictures, which are defined as a narrowing of the small or large intestine, can cause serious disruption to the digestive system. Symptoms can vary depending on the location and severity of the stricture, but commonly include nausea and vomiting, abdominal pain, bloating, and problems passing both gas and stool.

An esophageal stricture occurs when the esophagus narrows due to scarring of the lining. This scar tissue may be caused by chronic acid reflux and heartburn. While most esophageal strictures do not require clinical intervention, if left untreated those affected may experience difficulty in swallowing.

Fortunately, advancements in the medical field have made it possible to treat bowel or esophageal strictures through a variety of options such as endoscopy procedures or clinical trials involving drug therapy.

Contact us to learn more about current enrolling clinical trials.

NERD

NERD Non-Erosive Gastroesophageal Reflux Disease

NERD Non-Erosive Gastroesophageal Reflux Disease

Do you experience symptoms like heartburn, regurgitation, or difficulty swallowing? You may have gastroesophageal reflux disease (GERD), a condition where stomach acid flows back into the esophagus. But if you have these symptoms without any visible damage to the esophageal mucosal lining, you may have non-erosive gastroesophageal reflux disease (NERD).

Doctors can diagnose NERD with an endoscopy, where a camera is inserted into the esophagus to examine the tissue. If there is no damage to the esophageal lining, you may be diagnosed with NERD. It’s worth noting that NERD can range from mild to severe symptoms.

Research shows that around 50-85% of people with reflux-related symptoms but negative endoscopic findings are diagnosed with NERD. And more than two-thirds of all GERD patients have NERD. Accurate diagnosis and appropriate treatment for NERD are crucial to managing symptoms and preventing complications.

Don’t let NERD affect your quality of life. Talk to your doctor and contact Encore Borland Groover Clinical Research (EBGCR) to learn more about clinical trials for persistent reflux-related symptoms.

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Physician Investigator
Photo of Bharat K Misra M.D.
Gastroenterologist and Research Director Encore Borland Groover Clinical Research (EBGCR)
4800 Belfort Road Jacksonville FL 32256 Contact Research: 9046800871
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Colon Cancer Prevention

Irritable Bowel Syndrome (IBS)

Irritable Bowel Syndrome (IBS) Clinical Trial Information

Irritable Bowel Syndrome (IBS) – like symptoms may be caused by other digestive health issues. Gastroenterologists involved in clinical research are looking for new and better ways to help people manage chronic IBS-like symptoms.

The signs and symptoms of IBS can include:

  • cramping,
  • abdominal pain
  • bloating,
  • gas,
  • diarrhea
  • constipation

 

Did you know? Irritable bowel syndrome (IBS) negatively impacts quality of life for millions throughout the U.S.  Learn more about a new discovery for individuals experiencing chronic IBS-like symptoms.

Sign up to learn more!
Difficulty Swallowing and Eosinophilic Esophagitis EoE

Difficulty Swallowing EoE

Difficulty Swallowing EoE

Eosinophilic esophagitis (EoE) is a chronic disease of the esophagus. If you have EoE, white blood cells called eosinophils build up in your esophagus. EOE symptoms can cause damage and inflammation, causing pain, and may lead to difficulty swallowing, food getting stuck in your throat, or dysphagia.

If you have difficulty swallowing or symptoms of EOE, you should have symptoms reviewed by a gastroenterologist.

You may be eligible for a clinical research study if you have a confirmed diagnosis of eosinophilic esophagitis (EoE), eosinophilic gastritis, or eosinophilic duodenitis (EG/EoD).

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ClinicalTrials.gov Study Details

Eosinophilic Esophagitis
Clinical Research Protocol AK002-014 A Phase 2/3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of AK002 in Adult and Adolescent Patients with Active Eosinophilic Esophagitis

Photo of Ali Lankarani M.D.
Gastroenterologist Encore Borland Groover Clinical Research
4800 Belfort Road Jacksonville FL 32256 Contact Research: (904) 680-0871
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Photo of Michael Ibach MD
Gastroenterologist Encore Borland Groover Clinical Research
Contact Research: 9046800871
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Photo of Ben Pineau M.D., F.R.C.P.
Site Manager and Gastroenterologist Encore Borland Groover Clinical Research
100 Whetstone Place Suite 300 St. Augustine FL 32086 Contact Research: (904) 680-0871 Website: Contact Dr. Pineau
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Ulcerative Colitis EBGCR Clinical Research

Ulcerative Colitis

Ulcerative colitis

Ulcerative colitis (UC) is an autoimmune response that causes inflammation and ulcers (sores) in your digestive tract. UC usually affects the rectum and lower part of the colon.

Symptoms of ulcerative colitis can include: diarrhea, abdominal pain, weight loss, inflammation of the eyes and skin.


ClinicalTrials.gov Study Details

Stool Collection Study from Seres


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Physician Investigator

Photo of Bharat K Misra M.D.
Gastroenterologist and Research Director Encore Borland Groover Clinical Research (EBGCR)
4800 Belfort Road Jacksonville FL 32256 Contact Research: 9046800871
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Photo of Mark Fleisher M.D.
Gastroenterologist Encore Borland Groover Clinical Research
4800 Belfort Road Jacksonville FL 32256 Contact Research: 9046800871
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Recurrent C. Diff

Recurrent C. Diff

C. Difficile or Clostridioides difficile
CDIFF According to the CDC


Clostridioides difficile (also known as C. diff or CDIFF) is a bacterium that causes diarrhea and colitis (an inflammation of the colon).

It’s estimated to cause almost half a million illnesses in the United States each year.

About 1 in 6 patients who get C. diff will get it again in the subsequent 2-8 weeks.

Within a month of diagnosis, 1 in 11 people over age 65 died of a healthcare-associated C. diff infection.

PRISM-EXT: An Open-Label Extension of CP101 Trial Evaluating Oral FullSpectrum Microbiota® (CP101) in Subjects with Recurrence of Clostridium difficile Infection

Watch the recurrent C. Diff testimonial below.


Contact Research

Physician Investigator
Photo of Bharat K Misra M.D.
Gastroenterologist and Research Director Encore Borland Groover Clinical Research (EBGCR)
4800 Belfort Road Jacksonville FL 32256 Contact Research: 9046800871
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Fatty Liver/NASH

Fatty Liver/NASH

Non Alcoholic Steatohepatitis (NASH) is a type of fatty liver disease, characterized by inflammation of the liver with concurrent fat accumulation in liver.

NASH is closely related to the triple epidemic of obesity, pre-diabetes, and diabetes.  If you are living with NASH you may qualify for a clinical research study.  

Join Encore Borland Groover Clinical Research (EBGCR) for a complimentary Fibroscan test for fatty liver. 

ClinicalTrials.gov Study Details

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Photo of Ana Corregidor MD
Gastroenterologist Encore Borland Groover Clinical Research
4800 Belfort Road Jacksonville FL 32256 Contact Research: (904) 680-0871
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Photo of Michael Herman M.D.
Gastroenterologist Fleming Island Center for Clinical Research
1679 Eagle Harbor Parkway Suite D Fleming Island FL 32003 Contact Research: (904) 621-0390
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Photo of Linda Di Teodoro M.D.
Encore Borland Groover Clinical Research
4800 Belfort Road Jacksonville FL 32003 Contact Research: 904-680-0871
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